Laboratory for
Epigenome Inheritance
RIKEN IMS, Yokohama, Japan
Azusa Inoue, Ph.D.
2022- Team Leader at RIKEN IMS
2019- Visiting Associate Professor at Tokyo Metropolitan University
2018-22 YCI/Senior Scientist at RIKEN IMS
2012-18 Postdoc/Research Specialist at Harvard Medical School/Boston Children's Hospital, USA
2011-12 Postdoc at the University of North Carolina at Chapel Hill, USA
2011 Ph.D. at the University of Tokyo, Graduate School of Frontier Science
2006 Bachelor at Tokyo Metropolitan University
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Interview:
2022 Top Researchers (Japanese)
2020 理研NEWS (Japanese)
Chisayo Kozuka, Ph.D.
2023- Research scientist at RIKEN IMS
2020-23 Special Postdoctoral Researchers Program at RIKEN IMS
2018-20 Research scientist at RIKEN IMS
2016-18 Research fellow at Joslin Diabetes Center, Harvard Medical School, USA
2013-16 JSPS PD at University of the Ryukyus, Japan
2013 Ph.D. at University of the Ryukyus, Japan
2008 Bachelor at Health Sciences, Faculty of Medicine, Kyoto University
Selected publications
Kozuka, et al., Bromodomain inhibition reveals FGF15/19 as a target of epigenetic regulation and metabolic control. Diabetes, 2022 Jan 31;db210574. doi: 10.2337/db21-0574
Kozuka, et al., Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice. Diabetologia 2017; 60:1502
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Hailiang Mei, Ph.D.
2023- Research scientist at RIKEN IMS
2020-23 Postdoctoral Researcher at RIKEN IMS
2017-2019 Postdoc at Institute of Genetics and Developmental Biology, Chinese Academy of Sciences (CAS), China
2017 Ph.D at the Beijing Institute of Genomics, CAS, China
2010 Bachelor at Huazhong agricultural University, Wuhan, China
Selected publications
Mei H et al., H2AK119ub1 guides maternal inheritance and zygotic deposition of H3K27me3 in mouse embryos. Nat Genet 2021; 53, 539-550.
Qiu Q*, Mei H*, Deng X* et al., DNA Methylation Repels Targeting of Arabidopsis REF6. Nat Commun 2019; 10:2063
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Marino Maemura, Ph.D.
2023.4- JSPS Research Fellow RPD at RIKEN IMS
Selected publications
Maemura M, et al., (2021) Totipotency of mouse zygotes extends to single blastomeres of embryos at the four-cell stage. Sci Rep 11:11167.
Maemura M, et al., (2006) Inhibitory effect of c-Met mutants on the formation of branching tubules by a porcine aortic endothelial cell line. Cancer Sci. 97, 1343-50.
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Hiroto S. Fukushima, Ph.D.
2024- JSPS Research Fellow PD at RIKEN IMS
2023- Postdoctoral Researcher at RIKEN IMS
2021-23 Postdoc at Graduate School of Science, The University of Tokyo
2016-21 Ph.D. at Graduate School of Science, The University of Tokyo
2016 Bachelor at School of Science, The University of Tokyo
Selected publications
Fukushima H, et al., (2024) Cell cycle length governs heterochromatin reprogramming during early development in non-mammalian vertebrates. EMBO Rep 25(8):3300-23.
Fukushima H, et al., (2023) Incomplete erasure of histone marks during epigenetic reprogramming in medaka early development. Genome Res 33:572-586.
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Masahiro Matsuwaka, Graduate student
2024.4- RIKEN Junior Research Associate at RIKEN IMS
2021.4- Graduate student at Tokyo Metropolitan Univ/RIKEN IMS
2021.3 Bachelor at Tokyo Univ of Agriculture
Selected publications
Matsuwaka M, et al., (2025) H3K27 di-methylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos. Nat Cell Biol 27(1): 28-38
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Yuto Sekioka, Graduate student
2024.4- Graduate student at Tokyo Metropolitan Univ/RIKEN IMS
2024.3. Bachelor at School of Applied Biological Science, Hiroshima University
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Mami Kumon, Technical Staff
2022- Epigenome Inheritance Lab at RIKEN IMS
2019-22 Metabolic Epigenetics YCI Lab at RIKEN IMS
-2019 Developmental Genetics Lab at RIKEN IMS